Abstract
The patient was a 66-year-old woman who had developed systemic asymptomatic red papules for about 5 years before the initial consultation. Spontaneous recovery and recurrence of papules repeatedly occurred, and the individual papules disappeared spontaneously for about 10 days during the initial stage of the disorder. However, the interval of spontaneous recovery gradually continued several months thereafter. Pathohistological examinations demonstrated dense cellular infiltration, including large atypical CD30-positive cells, between the upper and middle layers of the dermis. Basedon the clinical course and biopsy findings, the patient was diagnosed as having lymphomatoid papulosis. Furthermore, immunostaining revealed that tumor cells fromthis patient were positive for fascin, indicating a risk to develop maligmant lymphoma. Therefore careful observation of clinical course is required in our patient. [Skin Cancer (Japan)2005; 20: 334-337]
