Abstract
Leiomyosarcomas, occurring in middle age and most commonly on the extremities, develop as solitary, painful or tender intra-or subcutaneous nodules showing a relatively benign biologic course. We reported a 39-year-old male with a subcutaneous tumor seen in the left arm region. Histological appearance of the tumor corresponded to cutaneous leiomyosarcoma, showing spindle-shaped atypical myomatous cells. Immunohistochemical studies demonstrated positivity of the tumor cells for α-smooth muscle actin and desmin. The leision was completely excised with wide margins. He has been free from recurrence or metastasis for thirteen months. [Skin Cancer (Japan) 2006; 21: 67-70]