Abstract
A 45-year-old woman had noticed a tumor on her right thigh for ten years. Since the tumor had increased in size during the past several months, she visited a doctor and complete surgical excision was performed. On histological examination, this tumor consisted of basaloid cells with eosinophilic cytoplasm and closer examination revealed numerous ductular structures. These ducts were highlighted by CEA and EMA immuno-staining suggesting that this tumor had a feature of eccrine differentiation. We performed a wide resection and right inguinal lymph node dissection. There were no distant metastases other than right inguinal lymph node metastasis. After the surgical treatment, three courses of low-dose FP therapy and two courses of FECOM therapy were performed. Two years after the excision, multiple small nodules and erythema developed on her right leg. The diagnosis of EPC with retrograde extension of wide-spread cutaneous metastasis was made. Palliative radiotherapy was employed without significant results, she died of DIC. [Skin Cancer (Japan) 2006; 21: 81-84]
