Abstract

A 76-year-old woman visited our department for the granulomatous tumor on her nose on October 6, 1992. She noticed a papule on her nose 5 months ago and it had gradually grown. A 16×12×3mm sized, oval shaped, ulcerated, pale pink colored, granuromatous tumor with slight bleeding was seen on her first visit. Spindle cell squamous cell carcinoma was diagnosed histologically for the tumor. The tumor was composed of mainly spindle-shaped cells with large, atypical, round nuclei and tumor cells arranged like a stream. Immunohistological staining of the tumor showed anti-keratin antibody positive, anti-melanoma antibody and vimentin both negative. The tumor cells was S-100 negative, however, plenty of S-100 positive dendric-shaped cells infiltrated among the tumor cells.