Abstract
Many investigators have performed oral food challenges with major allergenic foods (eggs, milk, etc.) in patients with atopic dermatitis (AD), and found that these foods could provoke aggravation of eczema in a limited number (less than 10%) of patients. It has thus been widely assumed that foods do not play an important role in the aggravation of AD. To supplement the previous studies, we recently performed oral food challenge tests with all foods consumed by patients with AD, and found that foods other than the major allergenic types (especially tree nut-related foods and fermented foods) provoked aggravation of eczema in approximately 44% of adults and 75% of children who showed unpredictable aggravation of AD, and 73% of breast-fed infants suffering from AD. Thus, it seems that foods (especially tree nut-related foods and fermented foods) play an important role in the aggravation of AD.Skin Research, 13: 65-75, 2014
