Abstract
A 37-year-old man had a dark red, pedunculated nodule measuring 20mm across the left side of the back. Histopathologically, the tumor was seen in the dermis and consisted of spindle-shaped cells. The tumor had multinucleated giant cells, extravasation of erythrocytes, hemosiderin, and cleft filled with erythrocytes. Immunohistochemically the tumor was positive for vimentin, partially positive for CD68, and negative for CD34, EMA, desmin, Melan-A, S-100 and HMB-45. On the basis of these findings, we diagnosed it as aneurysmal fibrous histiocytoma (AFH). Immunohistochemical examination should be helpful to distinguish AFH from malignant neoplastic diseases. SUVmax was slightly high, which was considered to be due to abundant fibroblasts in the tumor.Skin Research, 14: 85-88, 2015
