Abstract
A 24-year-old man presented at our hospital for the treatment of yellowish-white papules on the bilateral upper eyelids that had appeared four years earlier. Cryotherapy had been applied to the lesions several times, but the tumors had not disappeared. At the first presentation, we recognized a pea-sized flat-topped papule and a rice-sized rounded papule on his left and right upper eyelids, respectively. A biopsy specimen revealed minute calcified deposits in the upper and mid dermis. We diagnosed the lesions as subepidermal calcified nodules (SCNs) clinically and histopathologically. SCNs are usually treated by surgical excision, and have also been reported to be treated by CO2 laser. In the present case, two courses of CO2 laser treatments were applied to the lesions, which were subsequently successfully healed, leaving small scars and pigmentation. As SCNs tend to appear on the faces of young patients, the use of a CO2 laser is a cosmetically useful treatment for SCN.Skin Research, 14: 179-182, 2015