Abstract
Atopic dermatitis is common inflammatory skin disease. Although topical therapy forms the basis of treatment, some are intractable. Recently, ultraviolet irradiation has been employed to such intractable cases, and yielded a favorable clinical effect. The aim of this study was to investigate the efficacy and safety of the treatment with targeted 308-nm excimer light in atopic dermatitis and prurigo nodularis.
This is an observational study, and summarized the information of subjects with atopic dermatitis treated with 308-nm excimer light. Seventeen patients with atopic dermatitis, who showed resistance to topical steroid and oral antihistamines, were enrolled to this study. Irradiation was started from 150 or 300 mJ/cm2. If there was no adverse event, irradiation dose was occasionally increased by 20%. Irradiation with 308-nm excimer light was performed once a week for 2 months. Treatment effects are evaluated before treatment and 2 months after the initiation of treatment.
The results of this study suggest that 308-nm excimer light irradiation is effective in the treatment of atopic dermatitis. The 308-nm excimer light irradiation treatment would be worth trying to atopic dermatitis.Skin Research, Suppl. 23: 33-34, 2015
