Abstract
A 41-year-old male presented at our hospital with a 1-month history of two erythematous nodules on his chest and back, and a 1-week history of bilateral parotid swelling. A histopathological examination resulted in both lesions being diagnosed as non-caseating epithelioid granulomas. Magnetic resonance imaging showed swelling of the orbital part of the lacrimal glands and the parotid glands. Therefore, he was diagnosed with sarcoidosis, and the chest lesions were treated with topical corticosteroids. Three weeks after his first visit, right cheek dysesthesia appeared. We started administering oral corticosteroids (30mg/day prednisolone) and minocycline (100mg/day). At 1 week after the start of this treatment, the patient's parotid gland swelling had improved, and his dysesthesia improved over the next 2 weeks. Several mechanisms are known to cause neurological complications in sarcoidosis. In this case, the swelling of the lacrimal gland might have caused an increase in intraorbital pressure, leading to trigeminal nerve symptoms. This case demonstrates the importance of being aware of the clinical signs and symptoms of sarcoidosis, including parotid gland swelling and neurological manifestations, because it often requires oral corticosteroid treatment.Skin Research, 15: 265-269, 2016
