Abstract
A male in his 50s developed severe atopic dermatitis because he did not visit a clinic to receive regular treatment except when the dermatitis was aggravated and did not perform external treatment at home. In February 2016, he visited a doctor and was treated with oral cyclosporine. Thereafter, persistent high fever developed and the patient was hospitalized at the end of July for MSSA bacteremia. After his condition normalized, he was discharged from the hospital, but another episode of fever occurred shortly thereafter. In September, he was diagnosed with infectious endocarditis and referred to our institution for treatment. As the previous antibiotic therapy did not resolve the symptoms, we performed tricuspid valvuloplasty. Although the atopic dermatitis was severe, it was improved with standard topical steroid therapy. Infectious endocarditis is a serious disease associated with a variety of complications, some of which can result in death. It is characterized by persistent bacteremia. Severe atopic dermatitis may become a route for infection causing bacteremia. Although infectious endocarditis is less frequent, it must be kept in mind as a serious complication of atopic dermatitis. Moreover, it is important to note that improper or lack of treatment may result in serious infection.Skin Research, 16: 431-435, 2017
