Abstract
Ketonemia may be one of the etiologic factors of prurigo pigmentosa. We present an 18-year-old, non-diabetic female patient with prurigo pigmentosa that was preceded by loss of weight. Ketone bodies in blood were higher than normal, whereas urine ketone body was negative. After four-weeks treatment of oral minocycline (200 mg/day) skin lesions disappeared and normalization of blood ketone bodies followed. Our case suggested that ketonemia might be involved in the pathogenesis of prurigo pigmentosa.