Abstract
We report two cases of hypersensitivity syndrome due to anticonvulsants. Case 1 : A 50-year-old male had been suffered from epilepsy for a long time. Two months after he began to take carbamazepine, high grade fever, edema of his limbs and erythema on the whole body were developed. Case 2 : A month after a 54-year-old female began to take zonisamide for brain infarction, diarrhea, edema of body systemic, fever and erythema of whole body were developed. She had shock and DIC. Both cases got better with systemic steroid, but the erythema redeveloped during tapering. Both cases needed 2 and 5 months till they were free from steroid. The serum IgG titer of HHV-6 indicated high on both cases.
