Abstract
A 30-year-old woman was diagnosed systemic lupus erythematosus at the age of 14 years and treated with oral prednisolone. About 9 years later, 32 firm, slightly elevated, 3 to 20 mm in diameter, brown nodules were developed on the extremities, trunk and hip. Four of these lesions were excised. Histologic examination confirmed the diagnosis of dermatofibroma. Mucin deposited were found in the region between the fibrous lesion and the overlying epidermis. It was suggested that altered immune states in patients with autoimmune disorders could lead an outbreak of multiple dermatofibromas and the depositon of mucin.
