2021 Volume 20 Issue 4 Pages 314-319
A 65-year-old man visited a doctor 10years ago because an erythematous nodule appeared in a normal skin-colored plaque on his head that had been present since birth. Extensive resection and full-thickness skin grafting were performed at that time. The histopathological examination revealed that it was an apocrine adenocarcinoma that arose from the sebaceous nevus. One year prior to his first visit to our hospital, he noticed a subcutaneous nodule at the edge of the skin graft. The patient visited his previous doctor who noticed a swollen right clavicle lymph node. A diagnosis of recurrent apocrine adenocarcinoma with lymph node metastasis was made and he was referred to our department for further treatment. Extensive resection and right cervical lymph node dissection were performed. The histopathological examination revealed extranodal invasion of the cervical lymph nodes. Therefore, postoperative radiation and chemotherapy were administered. To date,after more than 3 years, no recurrence or metastasis has been observed. Several reports stated that apocrine adenocarcinomas can recur or metastasize after an extended period, demonstrating that long-term follow-up is required. However, an effective treatment for advanced-stage apocrine adenocarcinoma has not been established yet. We hope that more reports will be accumulated in the future. Skin Research, 20 : 314-319, 2021
