2022 Volume 21 Issue 2 Pages 138-143
A 73-year-old male presented with a 7 mm-sized pink nodule on the left upper lip. Dermoscopy demonstrated arborizing vessels. Atypical, spindle, or epithelioid cells were intermingled with fibrosis. Signet-ring cells were scattered. There was dPAS and Alcian blue-positive sialomucin in cytoplasm. Immunohistochemically, tumor cells were positive for CK7, CK20, and CDX2, and negative for TTF-1 and napsin A. The present case was diagnosed as metastatic carcinoma of the skin from gastric tube cancer. Endoscopy did not demonstrate gastrointestinal carcinomas. PETCT detected a tumor in the bottom of the right lung. He had undergone esophagectomy with gastric tube reconstruction for esophageal cancer at the age of 63, and had received gastric tube resection with jejunal interposition for gastric tube cancer at the age of 67. The gastric tube was elevated to the right thoracic cavity, and the final pathological diagnosis was poorly differentiated adenocarcinoma with serosal infiltration. We concluded that the gastric tube cancer had spread to the right lung directly, resulting in a hematogenous skin metastasis. Skin Research, 21 : 138-143, 2022
