2022 Volume 21 Issue 4 Pages 328-332
A 60-year-old woman had suffered from neck, chest and ankle joint pain for the past 10 years. Five years ago, she developed skin lesions on her palms and soles and was diagnosed with palmoplantar pustulosis. She continued to have recurrent episodes of skin inflammation and abscesses of the chest area, which were treated with incisional drainage and antibiotics following remissions and exacerbations. In our hospital, we also observed erythema, sensations of burning,swelling, fistula, and abscesses in the anterior thoracic region, indicating an increased inflammatory response. In addition, CT, MRI images, and bone scintigraphy revealed subcutaneous abscess, and accumulation on the bone, which led to the diagnosis of SAPHO syndrome. Administration of adalimumab for four months achieved marked improvement of skin and bone lesions. We experienced a case in which the patient did not improve with antimicrobial therapy and incisional drainage but improved markedly with adalimumab. Skin Research, 21 : 328-332, 2022
