A Case of Perianal Condyloma Lata in Men who Have Sex with Men

Abstract

A 35-year-old male presented with an erythematous rash on the trunk and small nodules in the perianal region as the chief complaint. He identied as men who have sex with men (MSM) and had sexual contact with several male partners during the past six months. At the rst clinical examination, tiny erythema was disseminated on the trunk and limbs, in addition to at-topped, red,small nodules in the perianal region. Syphilis serology showed high values. A skin biopsy was performed from a perianal nodule. Histopathological examination showed positive reactivity for Treponema pallidum by immunohistochemistry, conrming the diagnosis of condyloma lata. The erythematous rash was diagnosed as syphilitic roseola. He was administered oral amoxicillin 1,500 mg/day for six weeks, which initially achieved cure ; however, perianal condyloma acuminatum occurred two months later. Herein, we discuss the signicance of perianal condyloma in MSM with recurrent sexually transmitted infections based on current literature. Skin Research, 23 : 190-195, 2024