Abstract
A 45-year-old man noticed subcutaneous nodules on the forehead and the neck 5 months before the first visit. He had also a stomach tumor, which had been diagnosed as a leiomyosarcoma 2 months before the visit.
Biopsy specimens revealed that the tumors were composed of spindle shaped cells with pleomorphic nuclei. The tumor cells demonstrated positive staining for α-smooth muscle actin and negative for CD34 and KIT. Extensive clinical investigations revealed multiple metastatic tumors in the stomach, kidney and intestines. Then, skin tumors were diagnosed as skin metastasis of leiomyosarcoma.
Skin tumors increased in the number, and finally resulted in more than 40 mass lesions. The autopsy findings strongly suggested that a leiomyosarcoma originated from the left kidney and multiple metastases occurred to the skin.
