Abstract
Twenty cases with hypercalcemia, who were treated with calcipotriol (Dovonex®) ointment, were surveyed and risk factor of hypercalcemia was analyzed. Suspected risk factors are as follows : complication and history of renal disturbance, hypertension, hyperuricemia and diabetes ; combined administration of calcium, cyclosporin, etretinate, topical and systemic corticosteroid, other topical active vitamin D3 and emollient. Algorithm for prevention is presented.