Abstract
We report a case of intravascular papillary endothelial hyperplasia(IPEH)associated with venous hemangioma and thrombosis. A 19-year-old woman had noticed two mass lesions on the sole of the left foot about 2 years earlier. At the first examination the lesions were slightly elevated, elastic-hard subcutaneous nodules. For diagnosis and treatment, we excised the lesions under local anesthesia. Histopathologically the specimen showed venous hemangioma with many dilated thin-walled vessels. Papillary structures were lined by a single layer of endothelial cells and thrombosis was observed within the dilated lumen of the hemangioma. Based on these features, a diagnosis of IPEH associated with venous hemangioma with thrombosis was made. It is suggested that thrombus formation may play an important role in the pathogenesis of IPEH.
