Safety Study of Acne Treatment Cosmetics for Females with Facial Acne Vulgaris

Abstract

We carried out a four-week study in patients with facial acne vulgaris in order to assess the safety of new acne treatment cosmetics (a cream and a lotion) containing sulfur and dipotassium glycyrrhizate. We found adverse skin reaction in 5.2% of the subjects who used the acne treatment cream, and in 6.1% of the subjects who used the acne treatment lotion. These adverse skin reactions were slight or moderate, and there was no severe reaction. The average number of acne eruptions at 4 weeks was significantly decreased after application, compared with baseline. The satisfaction index for skin condition, obtained by using a visual analog scale, was improved after the study. The results indicate that the acne treatment cream and lotion are safe and useful for patients with acne.