Abstract
A 48-year-old woman was referred to Kobe-University Hospital with a 3-month history of a slowly increasing number of papules appeared on the labia majora of the vulva. A cervical carcinoma had been treated at the age of 28 by radical hysterectomy followed by radiotherapy and chemotherapy. Histological examination of the papule revealed a dilated lumen lined by a single layer of endothelial cells, which were positively stained with D2-40, a monoclonal antibody specific to lymphatic vessels, in the upper dermis, with overlying epidermal acanthosis and hyperkeratosis. From these findings we diagnosed this case as acquired lymphangiectasia.