Abstract
A 76-year-old man had been treated with docetaxel and nedaplatin chemotherapy for advanced lung adenocarcinoma (T2N2M1, stage IV). Since this chemotherapy was not effective, erlotinib monotherapy (150mg daily) was initiated. Eight days later, acneiform eruptions began to appear and were initially treated with nadifloxacin 1% cream. However, these eruptions worsened, and treatment with topical steroids was started. Strong topical steroids were used on the right side of the face, while the left side was treated with a milder version of this medication. After 2 weeks, the right face showed an improvement compared to the left face. The stronger class of steroids was then used to treat his entire face. Treatment with topical steroids caused the eruptions to disappear within 5 weeks without interrupting the erlotinib regimen. We think that it is better to treat adverse cutaneous effects associated with EGFR inhibitor without disrupting the treatment regimen.Skin Research, 9: 168-172, 2010
