Abstract
Dental implants are becoming popular, and there have been some reports of malignant tumors around dental implants. Although peri-implant risk factors include oral cancer and related radiotherapy history, mucosal lesions such as leukoplakia and lichen planus, drinking alcohol and smoking, the etiology is still unknown. We report a rare case of peri-implant squamous cell carcinoma arisen in the gingiva around the implant of the right upper molar 10 years after the placement. Furthermore, a systemic search is conducted using PubMed and Medline databases. A 74-year-old male presented with ulcerative lesions in the right upper molar gingiva. An oral examination revealed that there was 5×2.5 mm ulcerative lesion of the right upper second molar of palatal side gingiva. Radiographic examination showed two implants were placed in the right upper molar, and vertical bone resorption image was also found around the implant. As the pathology report documented the diagnosis of squamous cell carcinoma, partial maxillary resection was performed under general anesthesia. Eighteen months have passed since the operation, and there has been no recurrence and metastasis.