Abstract
Group B Streptococcus (GBS) is well-known to cause meningitis and sepsis in the neonatal period. Herein, we present a rare case of a full-term male neonate who developed early-onset sepsis by GBS delivered from a GBS screening negative mother. In last pregnancy, her GBS screening was positive, and she received antibiotics during her last delivery. Then, the child did not develop GBS infection. In this pregnancy, her GBS screening at the 10th and 36th week of gestation was negative, and antibiotics were not administered during this delivery. The child was born at 37 weeks of gestation and weighed 2930 g at birth. There were no signs of infection after birth, but he developed grunting and tachypnea at 7 hours after birth and was admitted to the neonatal intensive care unit. He was diagnosed with early-onset sepsis by GBS since GBS was identified in the blood culture. His symptoms were improved by the administration of ampicillin for 10 days and was discharged at 18 days of age without any developmental delay. It is important to manage a neonate after birth, keeping in mind that neonatal with GBS infection can develop even if the GBS screening is negative. The accumulation of the data of babies who are infected with early-onset GBS and GBS screening results of their mothers at pregnancy, including rare cases like ours, may provide better screening methods.
