Abstract
Authors critically reviewed the current chemical management in Japan, Europe and U.S.A. focusing on the interaction between “science” and “policy” which would affect in the chemical management. Risk assessment is one of the useful trendy tools for the chemical management. The chemical management should be based on the well-balanced regulations and self-initiatives. The regulation needs decision making which is always affected both by science and policy. The weight of science and policy is varied within countries because of the differences in history and culture of the society. What chemical management should be all about? What the interaction between science and policy should be all about? Compared with Europe and U.S.A., Japan seems to have a good compromise with science and policy in chemical management followed by decision making. This report will make a proposal to the good use of science in policy and also a proposal to the smarter chemical management.