A Case of Juvenile Heterochronous Bilateral Breast and Lung Cancer Diagnosed through Surveillance of Peutz-Jeghers Syndrome

Abstract

A patient was diagnosed with Peutz-Jeghers syndrome at the age of 27 years following the onset of intestinal accumulation due to hamartomatous polyps, who then underwent breast cancer surveillance. The patient was diagnosed with right breast cancer at 31 years of age. Furthermore, 3 years after undergoing right breast cancer surgery, left breast cancer was diagnosed during a routine examination. Computed tomography at the time of right breast cancer diagnosis showed ground-glass opacity in both lungs. During follow-up, the findings in the left lung indicated malignancy. Partial thoracoscopic resection was performed, and lung cancer was diagnosed. Although the effectiveness of surveillance for malignant tumors outside the gastrointestinal tract has not been established, we report a case in which we could diagnose juvenile heterochronic bilateral breast cancer and lung cancer through surveillance.