Journal of St. Marianna University
Online ISSN : 2189-0277
Print ISSN : 2185-1336
ISSN-L : 2185-1336
Original Article
Estimation of Possible Causes of Out-of-Hospital Cardiac Arrest Using the Modified Clinical Thrombolysis in Myocardial Infarction Risk and Agatston Score: A Retrospective Observational Study
Ayu MinouraToru YoshidaSatsuki YamazakiYoko KanamitsuYuri KonJunichi MatsumotoShigeki Fujitani
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JOURNAL FREE ACCESS

2022 Volume 13 Issue 1 Pages 9-21

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Abstract

Aim: It is often difficult to identify etiology of out-of-hospital cardiac arrest (OHCA) patients. This study aimed to detect OHCA patients with acute coronary syndrome (ACS) by Agatston score and modified clinical thrombolysis in myocardial infarction (TIMI) risk score (mc-T score).

Methods: A total of 414 patients with clear etiology from 2,614 OHCA were enrolled in this study. We divided these patients into two groups: OHCA patients by ACS (coronary definite group, n=82) and OHCA patients by other causes (non-coronary group, n=332). Agatston and mc-T scores were measured in these patients. Comparison between the two groups was performed to evaluate associations between these scores and with or without ACS.

Results: Agatston and mc-T scores were significantly higher in the coronary definite group than in the non-coronary group and were independent predictors of ACS in multivariate analysis. Either Agatston score ≥ 17.95 or mc-T score ≥ 2 revealed 89% of sensitivity to detect the coronary definite group which would allow for a relatively reliable screening of ACS. Regarding patients discharged from hospital due to death, both Agatston score ≥ 166.1 and mc-T score ≥ 2 revealed 98.3% of the specificity, which would allow for a relatively reliable inclusion of ACS.

Conclusion: Agatston and mc-T scores seemed to be useful methods for ruling in and out ACS in OHCA patients.

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© 2022 St. Marianna University Society of Medical Science
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