An Experimental Study of Cultured Epithelial Grafting Using Oral Mucosal Cells

Fabrication of Cultured Epithelium and its Morphological Analysis

Abstract

In this study, a new fabricating method of cultured epithelium using mucosal cells was established. This method was fundamentally based on that of cultured epithelium by Green et al. (1975). This cultured epithelium showed stratification and identical morphology to physiological mucosa. The mucosal cells possessed higher proliferating ability and maintained longer biological activity than that of epidermal cells. The most important morphological characteristics of mucosal cells was in its low grade differentiation and also it kept original mucosal structures. From these results, the usefulness of this cultured epithelium using mucosal cells was indicated for the mucosal transplantation.