1994 Volume 43 Issue 3 Pages 460-465
Multiple malignant tumors were found in 20 of the 224 patients with malignant tumor in the oral and maxillofacial region (8.93%), who received treatment at the Second Department of Oral and Maxillofacial Surgery, Niigata University Dental Hospital, from 1974 to 1992.
The results are as follows.
1. In the cases of multiple malignant tumors, double cancers were found in 16 and triple cancers in 4 patients. Fourteen of the 20 patients were males and six females (2.33: 1).
2. In the cases of double cancers, the average age of first cancers was 62.6 years and second cancers was 67.0 years. In these cases, non-synchronous cancers (an interval of more than one year) accounted for 81.2%.
accounted for 81.2%. 3. The other regions of the multiple malignant tumors were digestive and respiratory organs (83.3%). Especially, stomach, esophagus and lung together accounted for 62.5%.
4. 43.8% of the cases of double cancers had suffered from two cancers with an interval of more than 5 years. Consequently, the necessity of follow-up, at least more than 5 years, was revealed in the cases of malignant tumors of the oral and maxillofacial region.
