Journal of The Japanese Stomatological Society
Online ISSN : 2185-0461
Print ISSN : 0029-0297
ISSN-L : 0029-0297
A Case of Malignant Transformed Pleomorphic Adenoma
Hirokazu NAKAHARAKanemitsu SHIRASUNATakafumi OGURATakayoshi SAKAITokuzo MATSUYA
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1994 Volume 43 Issue 3 Pages 484-488

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Abstract

A tumor growing in the palate of a 72-year-old woman, which was extirpated about 30 months ago, showed histologically a pleomorphic adenoma consisting of uniform epithelial cells with myxoid stroma. The patient had a recurrent tumor showing progressive and infiltrative growth. The invasive tumor was widely excised and radiation therapy with a total of 56 Gy of linear accelerator was postoperatively given. Two years later, the patient had cervical lymph node and lung metastases and received surgical excision of these metastatic lesions. The patient is condition has been followed, and no further recurrence has occurred so far. The histopathological appearances of the recurrent and metastatic tumors were similar to those of the primary tumor except for a very mild anaplastic change of epithelial cells in the recurrent tumor and squamous metaplasia of tumor cells in the metastatic ones.

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