Abstract
This study was designed to examine the changes of the serum levels of lipid peroxide (LPO) and ceruloplasmin (CP), and the production of reactive oxygen species (ROS) of polymorphonuclear leukocytes (PMN) in postoperative inflammation. In this study, peripheral blood was obtained from thirteen patients with mandibular prognathism preoperatively and on day 1 and day 5 postoperatively and serum LPO, serum CP and luminol dependent chemiluminescence (CL) of PMN were measured, respectively. The results showed that CP concentration and CL significantly increased with the concomitant increase of PMN count on day 1 postoperatively. These parameters have showed a tendency to decrease on day 5 of postoperatively. However, the level of LPO in serum was not altered during observation. Furthermore, these parameters did not show any correlation with each other. These results indicate that, in noninfectious inflammation, LPO would not be accumulated because the host may not need to produce ROS. However, the host may keep the activate state of PMN to maintain homeostasis.
