1995 Volume 44 Issue 4 Pages 658-661
In a 56-year-old male with aplastic anemia of a 10-year history, a highly differentiated squamous cell carcinoma developed in the gingiva of the left mandibular molars (T3N0M0). Chemotherapy that causes marked bone marrow suppression was avoided; the surgery was limited to marginal resection of the mandible and dissection of the upper neck region to minimize the surgical damage, and radiation therapy (50 Gy) was performed postoperatively. The platelet level was maintained at 60, 000/μl or above for several days by preoperative platelet transfusion. It decreased to 10, 000/μl after the end of the radiation therapy but recovered gradually. The white blood cell count could be maintained at 3, 000/μl or above, and red blood cell count at 2.5 million/μl or above. The result was satisfactory.