Two cases of mammary analogue secretory carcinoma

Abstract

Mammary analogue secretory carcinoma （MASC） is a mammary secretory carcinoma like salivary gland tumor which was reported in 2010 by Skalova et al. Its histopathological features vary, but it displays similarities to acinic cell carcinoma. Around 30％ of acinic cell carcinoma cases diagnosed before the disease concept was established are now considered to be MASC. The main feature of MASC is the expression of ETV6-NTRK3 gene fusion. With a review of the literature, we report two surgical cases which were diagnosed as MASC after histopathological examination.