Clinical and histological study of nasopharyngeal carcinoma

Abstract

We analyzed the clinical and histological findings of 46 patients with nasopharyn geal carcinoma (NPC) treated at Saga University hospital between 1981 and 2004. The patient population included 35 men and 11women, aged 20 to 80 years (mean: 57 years). As primary treatment, eight patients received combination therapy of peplomycin followed by radiation; 22 patients received neo-adjuvant chemotherapy followed by radiation; 16 patients received CDDP-based concurrent chemo-radiotherapy. The five-year survival rate of all the patients was 46%. Compared to treatment with peplomycin followed by radiation, concurrent chemo-radiotherapy significantly increased five-year survival rate of patients with NPC.