Rapidly growing poorly differentiated adenocarcinoma of pancreatic remnant after resection of intraductal papillary-mucinous neoplasm (IPMN)

Abstract

A 78-year-old man was admitted to our hospital with the chief complaint of abdominal pain. Various imaging studies demonstrated multiple cystic lesions throughout the whole pancreas, and a mural nodule 5 mm in diameter in the body. Distal pancreatectomy was performed. Although histopathological examination revealed IPMN with mild atypia, the patient died because of poorly differentiated adenocarcinoma of the pancreatic stump that grew rapidly two years after distal pancreatectomy. We report a case of extremely aggressive IPMN that developed in the pancreatic remnant tissue.