Abstract
A total of 217 patients who underwent pancreatectomy for intraductal papillary mucinous neoplasm (IPMN) were investigated to evaluate the method of follow-up after surgical resection. The 5-year survival rate was 39% in patients with invasive IPMN. Liver metastasis and peritoneal dissemination were often recognized as the mode of tumor recurrence. Five patients (2.3%) underwent pancreatectomy again for a metachronous multifocal IPMN lesion in the remaining pancreas and 4 of these had a main duct IPMN. Furthermore, 32 patients (15%) had other malignant tumors in addition to synchronous or metachronous IPMN. We consider a close follow-up after surgical resection for IPMN is important, with special attention to tumor recurrence, especially invasive IPMN, metachronous multifocal IPMN in the remnant pancreas, and possible other malignant tumors associated with synchronous or metachronous IPMN.
