Glucagonoma syndrome; a case report with necrolytic migratory erythema

Abstract

We describe a 38-year-old woman with itching and eruption that had migrated from the lower legs to the upper body. The glucagon level was 2,100 pg/ml (upper limit of normal, 180 pg/ml). Computed tomographic scan of the abdomen revealed a 3.5 cm mass in the tail of the pancreas. The tumor was removed and found to be a glucagonoma. The clinical eruption resolved promptly and the glucagon level decreased to the normal range after surgical exision. The patient was alive with no recurrence 4 years after surgery.