The availability of autologous blood donation in pancreaticoduodenectomy for peri-ampullary cancer

Abstract

We introduced autologous blood donation(ABD) in pancreaticoduodenectomy for peri-ampullary cancer from September 2002. We classified 135 consecutive patients who underwent pancreaticoduodenectomy from January 2000 to April 2007 into pre-ABD and post-ABD groups. The pre-ABD group consisted of 38 patients from January 2000 to August 2002, and the post-ABD group consisted of 97 patients from September 2002 to April 2007. The patients' backgrounds, frequency of allogenic blood transfusion(ABT), and morbidity were compared in the two groups.
In the patients' backgrounds, only the amount of estimated operative blood loss (EBL) in the post-ABD group was significantly less than that in the pre-ABD group (p=0.0058). And the frequency of ABT significantly decreased from 61% in the pre-ABD group to 35% in the post-ABD group (p<0.0001).
In the result of the multiple logistic regression analysis, we identified the risk factors for requiring ABT was the presence of anemia in the pre-operative period (Hb<11g/dl) and excessive EBL of more than 1270ml.