Abstract
Anaplastic carcinoma of the pancreas is a relatively rare type of invasive ductal carcinoma. When detected, patients usually have huge tumors showing rapid growth and thus have a very poor prognosis. Intraductal papillary-mucinous neoplasm of the pancreas is sometimes accompanied by invasive ductal carcinoma. We herein report a case of anaplastic carcinoma of the pancreas coexisting with intraductal papillary-mucinous carcinoma (IPMC). A 78-year-old woman with acute heart failure and aortic stenosis was admitted to our hospital. Computed tomography accidentally revealed a tumor of the head of the pancreas. She first underwent aortic valve replacement for aortic stenosis, and computed tomography two months later inadvertently revealed a rapidly expanding tumor in the head of the pancreas. We performed subtotal stomach-preserving pancreaticoduodenectomy following diagnosis of the pancreatic carcinoma. The pathological diagnosis was anaplastic carcinoma of the pancreas coexisting with IPMC.