2013 Volume 28 Issue 2 Pages 156-162
In the international consensus guidelines 2012 for the management of IPMN and MCN of the pancreas, six histological aspects are discussed, (1) Types of invasive carcinoma of malignant IPMN, (2) Pathologic definition of minimally invasive carcinoma derived from IPMN, (3) Distinction and clinical relevance of gastric, intestinal, pancreatobiliary, and oncocytic forms of IPMNs, (4) Role of intraoperative frozen section evaluation in the surgical management of IPMNs, (5) Special instructions for specimen processing to differentiate BD-IPMN from MD-IPMN, (6) Distinction of carcinoma derived from and concomitant with an IPMN. According to these, there are two important points. One is a standardization of histopathological criteria of each pathologist, and the other is a standardization of pathological specimen-processing. It is necessary to approach to these aspects by cross-sectional effort.