Abstract
We report a case of anaplastic ductal carcinoma with ossification. A 61-year-old man was admitted to our hospital complaining of hematemesis. CT and MRI showed a sharply demarcated tumor 7cm in diameter at the tail of the pancreas. Hemorrhage, necrosis and calcifications were demonstrated on the inside of the tumor, a neoplasm of the pancreas was suggested and a distal pancreasectomy was performed. The pathological examination revealed that undifferentiated malignant cells with osteoclastic polynuclear giant cells and ossification were present in the tumor tissue. Immunohistochemical studies of tumor cells were positive for vimentin staining. Thus anaplastic carcinoma with osteoclast-like giant cells of the pancreas was diagnosed. Pancreatic neoplasms sometimes contain calcifications, however, it is very rare that ossification is seen in the tumor tissue.
