2019 Volume 34 Issue 5 Pages 195-205
Purpose: The purpose of this study was to investigate the short- and long-term outcomes after pancreatectomy for pancreatic ductal adenocarcinoma (PDAC) in octogenarians.
Methods: The medical records of 141 patients who underwent pancreatectomy for PDAC were retrospectively reviewed. The patients were divided into two groups: non-octogenarians (n=124) and octogenarians (n=17).
Results: The prevalence of comorbidities was significantly higher in octogenarian than non-octogenarian patients, and the performance status was significantly worse in octogenarians compared to non-octogenarians. However, 82% of octogenarians had a performance status of ≤ 1. There was no difference in the American Society of Anesthesiologists physical status (ASA-PS) between the 2 groups. The postoperative clinical courses were not different between the two groups. There were no significant differences in recurrence-free survival and overall survival between the 2 groups in univariate analysis. Age was not a significant independent factor for recurrence-free survival and overall survival in multivariate analysis.
Conclusions: Pancreatectomy for PDAC can be performed safely even in octogenarians based on an assessment of their general condition using the ASA-PS or performance status. The benefit of undergoing pancreatectomy for PDAC was the same for octogenarian and non-octogenarian patients.
