2020 Volume 35 Issue 4 Pages 242-249
WHO The classification of tumors of the digestive system was revised in 2019. There were no major changes in pancreatic ductal adenocarcinoma (PDAC), though there are several minor changes including the addition of invasive micropapillary carcinoma as a subtype of PDAC and a revision of the subtypes of undifferentiated carcinoma. However, the role of pathology is not limited to organizing tumor classifications. Pathology has multiple roles in clinical care and basic research for PDAC. In this article, the histopathological features, subtypes, precursor lesions, and characteristics of cancerous stroma of PDAC are described. The current situation and future directions concerning with EUS-FNA, TNM classification and evaluation of tumor regression after neoadjuvant therapy in resected pancreatic cancer are discussed.
