Current pathological diagnosis of and issues regarding serous cystic neoplasms, mucinous cystic neoplasms and solid pseudopapillary neoplasms

Abstract

The clinicopathological features of typical serous cystic neoplasms (SCN), mucinous cystic neoplasms (MCN), and solid pseudopapillary neoplasms (SPN) have been established, but pathological issues related to diagnosis and treatment remain. The majority of SCNs have a benign course, but it should be noted that detailed examination of the surgical specimens may reveal local extension/invasion. It is desirable to consider how to deal with MCNs when the ovarian-like stroma is unclear, and consider criteria for follow-up or indications for surgery. Studies of SPNs that metastasize and SPNs with high-grade malignant transformation are desired.