2021 Volume 36 Issue 4 Pages 238-244
The third revision of the International Consensus Guidelines for the management of intraductal papillary mucinous neoplasm (IPMN) of the pancreas will be discussed during the 26th Meeting of the International Association of Pancreatology 2022 in Japan. There are 7 points to be discussed. 1) Morphological aspects; definition and significance of mixed type IPMN. 2) Subtype classification; independent of oncocytic type. 3) Pathological diagnosis; non-invasive carcinoma and high-grade dysplasia, and the definition of malignancy. 4) Modification of the algorithm for the management of branch duct IPMN. 5) Modification of the factors of high-risk stigmata and worrisome features; threshold of the height of mural nodules. 6) Modification of the surveillance protocol of branch duct IPMN considering possible development of concomitant pancreatic ductal adenocarcinoma (PDAC). 7) Surveillance protocol after resection of IPMN focusing on the remnant pancreas; possible development of concomitant PDAC after resection of non-intestinal IPMN and monoclonal skip lesions after resection of main duct IPMN.