2023 Volume 38 Issue 2 Pages 138-146
Since many patients with pancreatic cancer are diagnosed at a time when the lesion is unresectable and present with a variety of symptoms at diagnosis, it is necessary to initiate interventions aimed at palliation of symptoms and improvement of quality of life in the early stages of the disease. In the Pancreatic Cancer Treatment Guideline 2022, clinical questions (CQs) were defined for approaches required for early palliative treatment in the treatment of patients with pancreatic cancer (mental and psychological care and advance care planning for patients with pancreatic cancer and their families, and the utility of communication skills training) and for symptom palliation (pain management, peripheral nerve damage control, cachexia, thrombosis and ascites management) in the treatment of patients with pancreatic cancer, respectively. Although there is insufficient evidence for any of the CQs, they are considered important in the management of patients with pancreatic cancer, and a systematic review resulted in recommendations.