Abstract
A 71-year-old Japanese male with liver cirrhosis due to hepatitis C virus infection showed a markedly elevated serum α -fetoprotein (AFP) concentration. Computed tomography (CT) revealed a hypervascular tumor compatible with hepatocellular carcinoma (HCC) in Couinaud's segment 4 (S4) in the liver. One month later, the tumor was enlarged and five months later, the serum AFP level began to decrease without any therapy. The tumor in S4 subsequently regressed over two months. Tumor stains were not observed in the S4 area on digital subtraction angiography (DSA) and the serum AFP level had decreased to within normal range. On admission, another hypervascular tumor was visualized in S5 by CT and the lesion was treated with transarterial chemoembolization (TAE) . After TAE treatment, there was no finding of HCC recurrence on CT for at least twenty months. This report describes a case of spontaneous regression of HCC with a second enlarged tumor, which was satisfactorily treated with TAE.
