Abstract
Escherichia coli is present in the intestinal tracts of warm-blooded animals. Since E. coli cells are released into the environment through feces, they have evolved to possess the ability to adapt various environments such as soil, river, and ocean. The ocean, in particular, is high in salt concentration, and it is a very severe environment for E. coli, but the E. coli adapted to the marine environment, which leads to its ability to gurvive. In this review, we discuss the adaptation mechanism of E. coli cell to a high salt environment. Furthermore, we interpret an outline about the production of useful materials that can be used for high salinity adaptation of E. coli.