Development of a rapid analytical system for glycans using a multistage tandem mass spectral database

— Toward an era where everyone can analyze glycan structure without specialist knowledge —

Abstract

Conducting glycan analysis requires expertise. This requirement has been a major bottleneck in the progress of glycomics. If glycan analysis can be done easily and rapidly without specialist knowledge, then the development of glycan functional analysis and associated applications is expected to accelerate. Here, we describe the construction of a multistage tandem mass spectral database, and a system for rapid glycan analysis that utilizes this database, as examples of infrastructure development for the advancement of glycoscience.